Product Description and Regulatory Context
Ryser Pre-Workout is alleged to be an advanced pre-training formula operating with the intention of enhancing endurance output and power output, especially during the execution of high-intensity exercise. The primary performance drivers contained in the formula are the dual-phase caffeine system and precursors for nitric oxide.
The caffeine system consists of 250 mg of caffeine anhydrous for rapid absorption and another 100 mg of ZumXR™ sustained-release caffeine so as to maintain energy without an abrupt drop-off. This dual-phase system is purported to maintain a neuromuscular advantage through prolonged training.
L-theanine is included to counter excessive catecholamine emission so that a more balanced response ensues upon psych stimulation. L-citrulline measurement stands at 4.5 g per serving bolstering nitric oxide generation, hence vasodilation, and thus nutrient delivery to muscle tissues.
The subject product is being manufactured in FDA-registered facilities under cGMP (21 CFR Part 111), which involves quality controls and labeling as per the legal requirements under 21 CFR 101. However, it is neither NSF Certified for Sport nor under the Informed Choice human certification that competitive athletes may require.
Compliance summary:
- Produced in cGMP in facilities registered with the FDA
- Transparent labeling with disclosures without proprietary blends
- No third-party purity or banned substance testing
Ingredients and Scientific Explanation
Stimulant Compound
Caffeine Anhydrous (250 mg): Rapid plasma absorption, has an effect on alertness, performance (in regard to exercise), resting with this caffeine dose close to the high dose of 3–6 mg/kg/d recommended for performance, according to the International Society of Sports Nutrition (ISSN).
ZumXR™ Extended-Release Caffeine (100 mg): Micro-encapsulated caffeine to provide a slow release of caffeine while minimizing energy crashes and to support adding multiple outputs for sessions longer than 90 minutes.
L-Theanine: Alpha brainwave modulator to help balance excessive action of the sympathomimetic nervous system and smooth the delivery of the stimulants.
Agent for Vasodilation and Pump
L-Citrulline (4.5 gram): L-citrulline supports arginine levels in the plasma, which can contribute to more nitric oxide available for vasodilation. This dosing matches the literature, which claims that doses of 4-6 g pre-exercise is effective to improve vascular function and muscle endurance.
Vaso Drive-AP (Godzilla): A peptide complex from casein hydrolysate related to flexibility of arteries and health of the endothelium.
Without Breakdown Performance and Endurance
Example Beta-Alanine:
It raises muscle carnosine, delaying fatigue during high intensity training. It is known to cause harmless paresthesia in some sensitive individuals.
Example Electrolytes (Pink Himalayan Salt):
Added sodium supports fluid balance and muscular contractions during prolonged exertion.
Example Additives and Flavoring Systems:
Artificial sweeteners sucralose and acesulfame potassium are included under the FDA recommended Acceptable Daily Intake (ADI).
Flavor systems are developed with compliant natural and artificial flavors, and colorants listed in 21 CFR 73 and 74.
Manufacturing Methods and Labeling Transparency
Ryse abides by cGMPs published by the FDA, thereby complying with lot specific traceability and expiration dating requirements. Ryse labels their product with full disclosure on ingredient amounts (by weight) and avoids using proprietary blends.
Ryse considers that federal truth-in-advertising regulations and claims substantiation guidelines published by the Federal Trade Commission (FTC) take precedence over proprietary blends.
However, without third party laboratory verification to ISO/IEC 17025 standards, there is no independent guarantee of purity nor assurance that banned substances are absent.
This report stipulation may exclude Ryse’s applicability for professional athletes because they are subject to World Anti-Doping Agency (WADA) testing protocols.
Effectiveness and Performance Notes
Independent testers have reported the energy onset of Ryse Pre-Workout occurs 20–30 minutes after ingestion providing continued cognitive focus and improved physical performance characteristics for up to three hours.
The convenience of a dual-phase caffeine system assists in avoiding the roller coaster effect of an energy drop associated with single-phase high stimulant products.
The inclusion of L-citrulline favors vascularity and muscle pump from resistance training as advised from anecdotal feedback and the research results around nitric oxide.
Beta-alanine allows for beneficial outcomes in repeated high intensity efforts but anecdotal evidence reflects some associates that find the paresthesia noted with beta-alanine to be bothersome.
The flavor reception is positive due to unique partnerships with mainstream beverage companies. However, the extremely sweet flavor may be off-putting for individuals that have taken other supplement products that were not as sweet.
Tolerance, Safety, and usage tips
With a total caffeine content of 350 mg, Ryse Pre-Workout is best suited for already tolerant stimulant users.
Recommendations include:
Start with a half serving to DE determine your own personal tolerance, and cardiovascular response. Avoid using other sources of caffeine and staying within the FDA’s recommended daily limit of 400 mg. Use 6-8 hours in advance of sleep to not disrupt circadian rhythms.
Refrain from using diagnosed cardiovascular disease, uncontrolled hypertension, or caffeine hypersensitivity or allergy.
Ryse Pre-Workout has a lot to offer, such as double-phase caffeine delivery, nitric oxide support, and label transparency.
However, when you evaluate Ryse against competitors such as Transparent Labs BULK and Kage Pre-Kage, Ryse does comparative or better stimulant efficacy but does not have certified approval.
Athletes may prefer competitors that obtained NSF Certified for Sport or Informed Choice verification if needed to assure banned substances will not be used.
The lack of certification does not suggest the use of banned substances but may be an impediment for regulated competition environments.
FAQ’s
What is the caffeine delivery mechanism?
Dual-phase (immeditate release from caffeine anhydrous and sustained release from ZumXR™; allowing for performance without abrupt decline in performance).
Are ingredient dosages within scientifically validated ranges?
Yes. Caffeine and L-citrulline dosages are evidence-based efficacy ranges based in peer reviewed literature.
Is ryse pre-workout made by regulations?
It is manufactured in a FDA registered cGMP facility with transparent labeling; it does not have third party certification.
Is it tolerant of high stimulant users?
Not for stimulant sensitivity. Heavy caffeine load, should start with low serving size to check.
Does it have pump supporting ingredients?
Yes. L-citrulline is included at 4.5 g! And in some flavors more VasoDrive-AP® will be part of the product and support nitric oxide mediated vasodilation.
How is this not a certified pre-workout?
It has fully transparent labeling (ingredient name, amount, dosed per serving); however, does not have NSF or Informed Choice certified that some competitive athletes may need.